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A project to develop human monoclonal antibodies (hmAbs) approved

Part of: GS Prelims and GS-II – Health & GS-III – Science and Technology

In News:

Council of Scientific and Industrial Research (CSIR) has approved a project to develop human monoclonal antibodies (hmAbs) through New Millennium Indian Technology Leadership Initiative (NMITLI) programme.
These antibodies can neutralize SARS-CoV-2 in patients.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for causing coronavirus disease (COVID-19).

Key takeaways:

hmAbs shall be generated from convalescent phase of COVID-19 patients.
High affinity and neutralizing antibodies shall be selected.
The project aims to anticipate future adaptation of the virus and generate hmAbs clones that can neutralize the mutated virus and combat future SARS-CoV infections.

Important value additions:

New Millennium Indian Technology Leadership Initiative (NMITLI)

It is the largest public-private-partnership effort within the Research & Development field in the country.
It seeks to act as a catalyst in innovation-centered scientific and technological developments.
It also aims to help Indian industry achieve a global leadership position.

Monoclonal antibodies (mAb or moAb)

They are antibodies that are made by identical immune cells that are all clones of a unique parent cell.
They can have monovalent affinity, in that they bind to the same epitope (the part of an antigen that is recognized by the antibody).

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