fbpx

Blocking Factor D Protein may reduce inflammatory reactions associated with Covid-19

  • IASbaba
  • October 13, 2020
  • 0
UPSC Articles
Print Friendly, PDF & Email

Blocking Factor D Protein may reduce inflammatory reactions associated with Covid-19

Part of: GS Prelims and GS-III – Biotechnology

In news

  • A new study by Johns Hopkins Medicine researchers suggests that blocking a human protein factor D may reduce the deadly inflammatory reactions that many patients have due to COVID-19.

Key takeaways

  • Team focused on two proteins, factor H and factor D.
  • These are known as “complement” proteins.
  • They help the immune system clear pathogens from the body.
  • The researchers discovered that Covid-19’s spike protein causes factor D to overstimulate the immune response, which in turn prevents factor H from mediating that response.
  • When SARS-CoV-2 attacks the ACE2 receptors to proliferate and infect more cells in the human body, it also prevents Factor H from using the sugar molecule to bind with cells.
  • The team found that by blocking factor D, they were able to stop the destructive chain of events triggered by SARS-CoV-2.

For a dedicated peer group, Motivation & Quick updates, Join our official telegram channel – https://t.me/IASbabaOfficialAccount

Search now.....