IASbaba Daily Prelims Quiz
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The Current Affairs questions are based on sources like ‘The Hindu’, ‘Indian Express’ and ‘PIB’, which are very important sources for UPSC Prelims Exam. The questions are focused on both the concepts and facts. The topics covered here are generally different from what is being covered under ‘Daily Current Affairs/Daily News Analysis (DNA) and Daily Static Quiz’ to avoid duplication. The questions would be published from Monday to Saturday before 2 PM. One should not spend more than 10 minutes on this initiative.
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Question 1 of 5
1. Question
Consider the following statements regarding the TribeX Platform:
- It has been launched by the Ministry of Tribal Affairs as a digital learning ecosystem for preserving and promoting tribal knowledge systems.
- It integrates both a Learning Management System (LMS) and a Repository Management System.
- The platform presently offers only UGC-recognised postgraduate degree programmes in tribal studies.
- An MoU has been signed with Sampurnanand Sanskrit University, Varanasi, for offering hybrid postgraduate diploma programmes.
Which of the statements given above are correct?
Correct
Solution (a)
Explanation
- Statements 1, 2 and 4 are correct. TribeX is a first-of-its-kind digital learning platform launched by the Ministry of Tribal Affairs to preserve, promote and disseminate India’s tribal languages, arts, crafts, traditional knowledge and livelihoods. It integrates both a Learning Management System (LMS) and a Repository Management System, with a digital heritage archive containing thousands of multimedia resources. An MoU with Sampurnanand Sanskrit University, Varanasi enables the offering of UGC-recognised one-year hybrid postgraduate diploma programmes in subjects such as Santali (Ol Chiki), tribal textiles and museum management.
- Statement 3 is incorrect because the platform offers 20 free certificate courses in addition to diploma programmes; it does not offer only postgraduate degree programmes.
Why this question?
Tests implementing ministry, platform features and academic offerings through subtle factual traps.
Why important for UPSC?
Links tribal welfare, digital governance and cultural preservation under one initiative.
PYQ Pattern Link
Similar to UPSC questions on DIKSHA, SWAYAM, Bhashini and other digital education initiatives.
Incorrect
Solution (a)
Explanation
- Statements 1, 2 and 4 are correct. TribeX is a first-of-its-kind digital learning platform launched by the Ministry of Tribal Affairs to preserve, promote and disseminate India’s tribal languages, arts, crafts, traditional knowledge and livelihoods. It integrates both a Learning Management System (LMS) and a Repository Management System, with a digital heritage archive containing thousands of multimedia resources. An MoU with Sampurnanand Sanskrit University, Varanasi enables the offering of UGC-recognised one-year hybrid postgraduate diploma programmes in subjects such as Santali (Ol Chiki), tribal textiles and museum management.
- Statement 3 is incorrect because the platform offers 20 free certificate courses in addition to diploma programmes; it does not offer only postgraduate degree programmes.
Why this question?
Tests implementing ministry, platform features and academic offerings through subtle factual traps.
Why important for UPSC?
Links tribal welfare, digital governance and cultural preservation under one initiative.
PYQ Pattern Link
Similar to UPSC questions on DIKSHA, SWAYAM, Bhashini and other digital education initiatives.
-
Question 2 of 5
2. Question
Consider the following statements regarding Hemophagocytic Lymphohistiocytosis (HLH):
- It is a hyperinflammatory syndrome caused by uncontrolled activation of immune cells.
- Primary HLH is caused by inherited genetic mutations, whereas secondary HLH may be triggered by infections, malignancies or autoimmune diseases.
- Epstein–Barr Virus (EBV) infection is among the recognised triggers of secondary HLH.
- HLH affects only the lymphatic system and does not involve the liver, spleen or bone marrow.
Which of the statements given above are correct?
Correct
Solution (c)
Explanation
- Statements 1, 2 and 3 are correct. Hemophagocytic Lymphohistiocytosis (HLH) is a rare, life-threatening hyperinflammatory syndrome caused by uncontrolled activation of immune cells, resulting in excessive cytokine production and tissue damage. Primary (familial) HLH arises due to inherited genetic mutations, whereas secondary HLH may be triggered by infections such as Epstein–Barr Virus (EBV), autoimmune diseases, malignancies (especially lymphomas) or certain drugs.
- Statement 4 is incorrect because HLH commonly affects the bone marrow, liver, spleen, lymph nodes and even the brain, potentially causing multi-organ failure if untreated.
Why this question?
Tests distinction between genetic and acquired immune disorders.Why important for UPSC?
Rare diseases and immunology are emerging science topics.PYQ Pattern Link
Similar to UPSC questions on autoimmune diseases and viral disorders.Incorrect
Solution (c)
Explanation
- Statements 1, 2 and 3 are correct. Hemophagocytic Lymphohistiocytosis (HLH) is a rare, life-threatening hyperinflammatory syndrome caused by uncontrolled activation of immune cells, resulting in excessive cytokine production and tissue damage. Primary (familial) HLH arises due to inherited genetic mutations, whereas secondary HLH may be triggered by infections such as Epstein–Barr Virus (EBV), autoimmune diseases, malignancies (especially lymphomas) or certain drugs.
- Statement 4 is incorrect because HLH commonly affects the bone marrow, liver, spleen, lymph nodes and even the brain, potentially causing multi-organ failure if untreated.
Why this question?
Tests distinction between genetic and acquired immune disorders.Why important for UPSC?
Rare diseases and immunology are emerging science topics.PYQ Pattern Link
Similar to UPSC questions on autoimmune diseases and viral disorders. -
Question 3 of 5
3. Question
Which one of the following clinical features is most characteristic of Hemophagocytic Lymphohistiocytosis (HLH)?
Correct
Solution (a)
Explanation
Option (a) is correct. HLH is characterised by an overactive immune response, where cytotoxic T cells and macrophages become excessively activated, producing large amounts of inflammatory cytokines—a phenomenon often referred to as a cytokine storm.
This excessive inflammation can damage multiple organs including the liver, spleen, bone marrow and brain. Option (b) describes Type 1 Diabetes Mellitus, option (c) refers to Multiple Sclerosis, while option (d) describes Amyotrophic Lateral Sclerosis (ALS).
UPSC frequently tests the ability to distinguish diseases based on their underlying pathophysiology rather than merely recognising their names.
Why this question?
Focuses on disease mechanism rather than symptoms.Why important for UPSC?
Conceptual medicine questions are increasingly asked.PYQ Pattern Link
Comparable to UPSC questions on cytokine storms and autoimmune disorders.Incorrect
Solution (a)
Explanation
Option (a) is correct. HLH is characterised by an overactive immune response, where cytotoxic T cells and macrophages become excessively activated, producing large amounts of inflammatory cytokines—a phenomenon often referred to as a cytokine storm.
This excessive inflammation can damage multiple organs including the liver, spleen, bone marrow and brain. Option (b) describes Type 1 Diabetes Mellitus, option (c) refers to Multiple Sclerosis, while option (d) describes Amyotrophic Lateral Sclerosis (ALS).
UPSC frequently tests the ability to distinguish diseases based on their underlying pathophysiology rather than merely recognising their names.
Why this question?
Focuses on disease mechanism rather than symptoms.Why important for UPSC?
Conceptual medicine questions are increasingly asked.PYQ Pattern Link
Comparable to UPSC questions on cytokine storms and autoimmune disorders. -
Question 4 of 5
4. Question
Consider the following statements regarding the treatment of Hemophagocytic Lymphohistiocytosis (HLH):
- Corticosteroids and immunosuppressive therapy constitute important components of treatment.
- Hematopoietic stem cell transplantation may be considered in selected patients.
- Broad-spectrum antibiotics alone are sufficient to cure both primary and secondary HLH.
- Early diagnosis significantly improves clinical outcomes.
Which of the statements given above are correct?
Correct
Solution (a)
Explanation
- Statements 1, 2 and 4 are correct. Treatment of HLH aims to suppress the excessive immune response using corticosteroids, immunosuppressive drugs, chemotherapy and biologic agents. In selected patients—particularly those with primary (familial) HLH—hematopoietic stem cell transplantation may provide a definitive cure. Since the disease progresses rapidly, early diagnosis and treatment are crucial to prevent irreversible organ damage and reduce mortality.
- Statement 3 is incorrect because antibiotics may treat associated bacterial infections but cannot control the underlying immune dysregulation responsible for HLH.
Why this question?
Tests understanding of disease management and prognosis.Why important for UPSC?
Healthcare advances and rare disease therapies are relevant.PYQ Pattern Link
Similar to UPSC conceptual questions on stem-cell therapy.Incorrect
Solution (a)
Explanation
- Statements 1, 2 and 4 are correct. Treatment of HLH aims to suppress the excessive immune response using corticosteroids, immunosuppressive drugs, chemotherapy and biologic agents. In selected patients—particularly those with primary (familial) HLH—hematopoietic stem cell transplantation may provide a definitive cure. Since the disease progresses rapidly, early diagnosis and treatment are crucial to prevent irreversible organ damage and reduce mortality.
- Statement 3 is incorrect because antibiotics may treat associated bacterial infections but cannot control the underlying immune dysregulation responsible for HLH.
Why this question?
Tests understanding of disease management and prognosis.Why important for UPSC?
Healthcare advances and rare disease therapies are relevant.PYQ Pattern Link
Similar to UPSC conceptual questions on stem-cell therapy. -
Question 5 of 5
5. Question
Consider the following statements regarding cytokine storm:
- It results from excessive activation of the immune system leading to uncontrolled release of inflammatory cytokines.
- It may occur in severe viral infections as well as disorders like HLH.
- It invariably indicates bacterial septicaemia and is unrelated to immune dysregulation.
- Excessive cytokine release can contribute to multi-organ dysfunction.
Which of the statements given above are correct?
Correct
Solution (d)
Explanation
- Statements 1, 2 and 4 are correct. A cytokine storm refers to an uncontrolled release of inflammatory cytokines due to excessive immune activation. It is seen in disorders such as HLH, severe viral infections (including severe COVID-19), and certain immunological conditions. Excessive cytokine production damages tissues, increases vascular permeability and may culminate in multi-organ dysfunction.
- Statement 3 is incorrect because cytokine storms are not limited to bacterial septicaemia; they represent a broader phenomenon of immune dysregulation occurring in several infectious and non-infectious conditions.
UPSC increasingly frames questions linking disease mechanisms with current medical developments.
Why this question?
Integrates immunology with current health affairs.Why important for UPSC?
Mechanism-based science questions have become common in recent Prelims.PYQ Pattern Link
Comparable to UPSC conceptual questions on immune response and infectious diseases.Incorrect
Solution (d)
Explanation
- Statements 1, 2 and 4 are correct. A cytokine storm refers to an uncontrolled release of inflammatory cytokines due to excessive immune activation. It is seen in disorders such as HLH, severe viral infections (including severe COVID-19), and certain immunological conditions. Excessive cytokine production damages tissues, increases vascular permeability and may culminate in multi-organ dysfunction.
- Statement 3 is incorrect because cytokine storms are not limited to bacterial septicaemia; they represent a broader phenomenon of immune dysregulation occurring in several infectious and non-infectious conditions.
UPSC increasingly frames questions linking disease mechanisms with current medical developments.
Why this question?
Integrates immunology with current health affairs.Why important for UPSC?
Mechanism-based science questions have become common in recent Prelims.PYQ Pattern Link
Comparable to UPSC conceptual questions on immune response and infectious diseases.
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